Full project title: “High-throughput high-resolution quantitative phase microscopy and tomography with spatiotemporal coherence engineering for non-invasive single-cell analysis”.

Cells are the fundamental units defining the structure and functions of living organisms. This project addresses one of the key challenges in cell research: rapid and non-destructive imaging of entire cell populations with subcellular accuracy. The project focuses on developing new fundamental theories, optoelectronic systems, and reconstruction algorithms to enable label-free, high-resolution quantitative phase imaging (2D imaging) with a large field of view and refractive index tomography (3D imaging). These will be based on the engineering of illumination coherence (synthesizing coherent and incoherent light techniques). The goal is to experimentally and numerically drive improvements in the signal-to-noise ratio and overcome classical information throughput limitations of currently available commercial phase microscopy systems.

Principal Investigator: Prof. Maciej Trusiak

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