NaNoLens project aims to develop lensless holotomographic nanoscopy in deep UV (DUV) for imaging living cells with high resolution, without the use of fluorescent markers. While the lensless technique enables a large field of view, current systems have limited spatial resolution. Using the DUV band with low illumination intensity we will overcome these limitations, enabling submicron-level imaging. The project’s innovation lies in applying DUV not for sterilization but for non-invasive studies of extracellular vesicle dynamics in living cell cultures, opening new opportunities for understanding and utilizing them. NaNoLens combines bioimaging, computational microscopy, and digital holography to create a compact, easy-to-implement tomography system for large volumes (lensless and dye-free), capable of functioning both in and outside the laboratory.

Principal Investigator: Prof. Maciej Trusiak 

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